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Guanabenz
go.drugbank.com/drugs/DB00629ApprovedWithdrawnGuanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMalic acid
go.drugbank.com/drugs/DB12751InvestigationalMalic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension.
Mixtures: Aminoven Infant 10% w/v, AKE 1100 GLUKOZLU IV SOLOSYONU, 500 MLIbudilast
go.drugbank.com/drugs/DB05266Investigational(codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan. … Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume
Bendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigationalA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.
Penicillamine
go.drugbank.com/drugs/DB00859ApprovedInvestigationalPenicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). … It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Categories: Compounds used in a research, industrial, or household settingGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigationalGlatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. … [A248870] Originally, glatiramer acetate was designed as a stimulant of myelin basic protein (MBP), a myelin antigen involved in the development of multiple sclerosis (MS), to induce experimental autoimmune
Synonyms: (T,G)-A-LGlyceryl monostearate
go.drugbank.com/drugs/DB11250ApprovedGlycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Mixtures: Cho-A Care Lot 1%Crofelemer
go.drugbank.com/drugs/DB04941ApprovedInvestigationalCrofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree <i>Croton lechleri</i>.
Categories: Compounds used in a research, industrial, or household settingHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalDopamine-antagonizing medications such as haloperidol are though to improve psychotic symptoms and states that are caused by an over-production of dopamine, such as schizophrenia, which is theorized to … However, this class of drugs is also limited by the development of movement disorders induced by dopamine-blockade such as drug-induced parkinsonism, akathisia, dystonia, tardive dyskinesia, as well as
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, γ-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenoneOctamoxin
go.drugbank.com/drugs/DB09249ApprovedWithdrawnThis drug was used in the past as an antidepressant agent in the 1960s, however, has since been discontinued. … Octamoxin, also known as _2-octylhydrazine_, is both an irreversible and nonselective monoamine oxidase enzyme inhibitor (MAOI) of the _hydrazine_ chemical class.