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Proctalgia
go.drugbank.com/conditions/DBCOND0011601Drugs: NifedipineSynonyms: Rectal pain, Pain rectalPancrelipase amylase
go.drugbank.com/drugs/DB11065ApprovedInvestigational[L2512] The pancrelipase mixture, including pancrelipase amylase, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510] … [L2509] The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch into more available saccharide forms.
Mixtures: Pancrease Mt 20, Cotazym Ecs 20Benzoic acid
go.drugbank.com/drugs/DB03793ApprovedInvestigationalThis leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. … It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
Mixtures: SKINOREN %20 KREM, 30 G, ARTU 100 ML SURUPCategories: Compounds used in a research, industrial, or household settingAcetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978. … [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703]
Categories: Compounds used in a research, industrial, or household settingProtein RecA
go.drugbank.com/bio_entities/BE0001269TargetMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...
Polypeptides: Protein RecATecovirimat
go.drugbank.com/drugs/DB12020ApprovedInvestigational[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. … [L3626, L3614] Tecovirimat was later approved by Health Canada in December 2021,[L39397] followed by the approval from the European Commission in January 2022.
Deserpidine
go.drugbank.com/drugs/DB01089ApprovedWithdrawnDeserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure
Synonyms: (3β,16β,17α,18β,20α)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl esterArdeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnIts molecular weight ranges from 2000 to 15,000 with an average molecular weight of 5500 to 6500. Normiflo was withdrawn from the US market in March 2000.
Diamine oxidase [copper-containing]
go.drugbank.com/bio_entities/BE0000351TargetEnzymeHumansCatalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:12072962, PubMed:19764817, PubMed:239684, PubMed:8144586). Its preferred substr...
Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1Copper transport protein ATOX1
go.drugbank.com/bio_entities/BE0002833TargetCarrierHumansMultifunctional copper-sensing protein that operates both as a cytosolic copper chaperone and as a copper-dependent transcription factor. … In the cytosol, transfers copper to the copper-transporting ATPase ATP7A at the trans-Golgi network, which is required for activation of secretory copper enzymes including lysyl oxidase (LOX) and SOD3.
Polypeptides: Copper transport protein ATOX1