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Displaying results 2471 - 2480 of 10000 in total
  1. Drug

    Purvalanol A

    go.drugbank.com/drugs/DB04751
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine, Purvalanol A
  2. Drug

    Atilotrelvir

    go.drugbank.com/drugs/DB19439
    Investigational

    Atilotrelvir is under investigation in clinical trial NCT05041907 (Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)).

    Synonyms: Spiro[2-azabicyclo[2.2.1]heptane-5,1′-cyclopropane]-3-carboxamide, N-[(1S)-1-cyano-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]-2-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-, (1S,3S,4R)-, (1R,4S,6S)-N-{(1S)-1-ciano-2-[(3S)-2-oxopirrolidin-3-il]etil}-5-[(2S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)butanoil]-5-azaespiro[biciclo[2.2.1]heptano-2,1'-ciclopropano]-6-carboxamida
  3. Drug

    Tryptamine

    go.drugbank.com/drugs/DB08653
    Investigational

    Synonyms: 2-(3-indolyl)ethylamine, 3-(2-Aminoethyl)indoleCategories: Heterocyclic Compounds, 2-Ring, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  4. Drug

    (R)-methylmalonyl-CoA

    go.drugbank.com/drugs/DB04045
    Investigational

    Synonyms: (R)-2-Methyl-3-oxopropanoyl-CoA, (R)-2-Methyl-3-oxopropionyl-CoACategories: Heterocyclic Compounds, 2-Ring, Thioesters of coenzyme A
  5. Drug

    Ziritaxestat

    go.drugbank.com/drugs/DB15403
    Investigational

    Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)-(methyl)amino)-4-(4-fluorophenyl)-thiazole-5-carbonitrile
  6. Drug

    Flutafuranol F-18

    go.drugbank.com/drugs/DB18825
    Experimental

    Synonyms: 2-(2-(18f)fluoro-6-(methylamino)pyridin-3-yl)-1-benzofuran-5-ol, 5-benzofuranol, 2-(2-(fluoro-18f)-6-(methylamino)-3-pyridinyl)-
  7. Drug

    Esmirtazapine

    go.drugbank.com/drugs/DB06678
    Investigational

    This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. … Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology.

    Categories: Adrenergic alpha-2 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine
  8. Drug

    Salsalate

    go.drugbank.com/drugs/DB01399
    ApprovedInvestigational

    Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. … A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis in the body. The parent compound has an elimination half-life of about 1 hour.

    Categories: Non COX-2 selective NSAIDSSynonyms: 2-Carboxyphenyl salicylate, o-Salicylsalicylic acid
  9. Drug

    Fludalanine

    go.drugbank.com/drugs/DB20846
    Experimental

    Fludalanine is a small molecule drug. Fludalanine has a monoisotopic molecular weight of 108.04 Da.

    Synonyms: 3-fluoro-d-alanine-2-d, D-alanine-2-d, 3-fluoro-
  10. Drug

    Naporafenib

    go.drugbank.com/drugs/DB18865
    Investigational

    Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-pyridinecarboxamide, n-(3-(2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl)-4-methylphenyl)-2-(trifluoromethyl)-)-, N-(3-(2-(hydroxyethoxy)-6-(morpholin-4-yl) pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine-4-carboxamide