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Vidarabine
go.drugbank.com/drugs/DB00194ApprovedWithdrawnA nucleoside antibiotic isolated from Streptomyces antibioticus. … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the
Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleosides and Nucleotides Excl. Reverse Transcriptase InhibitorsCrinecerfont
go.drugbank.com/drugs/DB18518ApprovedInvestigational[A264818] The majority of the poor health outcomes in patients with CAH result from the inability to precisely titrate glucocorticoid dosages to both adequately replace the deficiency and sufficiently … [A264818] Standard therapy involves cortisol replacement, but typically requires supraphysiological glucocorticoid doses to lower both ACTH and adrenal androgens, resulting in chronic glucocorticoid overexposure
Tafenoquine
go.drugbank.com/drugs/DB06608ApprovedInvestigationalTafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group. … [A35690] Tafenoquine was further developed collaboratively between GlaxoSmithKline and Medicines for Malaria Venture.[A35677] It was FDA approved on July 20, 2018.[L3770]
Categories: Antiparasitic Products, Insecticides and RepellentsChymopapain
go.drugbank.com/drugs/DB06752ApprovedWithdrawnChymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982.
Categories: Enzymes and CoenzymesPalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalits class approved for this use by the U.S. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Categories: Alimentary Tract and Metabolism, Antiemetics and AntinauseantsAllogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15731InvestigationalThese cells are CD362 enriched umbilical cord-derived mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and adult mesenchymal stem cells (MSCs); this … ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord.
Dermatophyte Infection
go.drugbank.com/conditions/DBCOND0139636Drugs: Amorolfine · Beclomethasone dipropionate · Bifonazole · Boric acid · Chloroxine · Chlorquinaldol +15 moreSynonyms: Dermatomycosis, other and unspecifiedSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigational[A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to treat renal carcinoma and differentiated thyroid carcinoma … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Categories: Alimentary Tract and Metabolism, magaldrate and antiflatulentsStabilin-2
go.drugbank.com/bio_entities/BE0004948TargetHumansBinds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. … The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS
Synonyms: FAS1 EGF-like and X-link domain-containing adhesion molecule 2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2