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Displaying results 2481 - 2490 of 10000 in total
  1. Drug

    NS-398

    go.drugbank.com/drugs/DB14060
    Experimental

    NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.

    Synonyms: N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide
  2. Drug

    Darigabat

    go.drugbank.com/drugs/DB18966
    Investigational

    Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine, 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)-
  3. Drug

    Serplulimab

    go.drugbank.com/drugs/DB17451
    ApprovedInvestigational

    Serplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa.
  4. Drug

    gamma-Butyrolactone

    go.drugbank.com/drugs/DB04699
    ExperimentalIllicit

    One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. … It is also used as a pharmacological agent and solvent.

    Categories: Compounds used in a research, industrial, or household setting, 4-ButyrolactoneSynonyms: 4-butyrolactone, 4-hydroxybutyric acid lactone
  5. Drug

    Zinc dibutyldithiocarbamate

    go.drugbank.com/drugs/DB14194
    Approved

    Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.

    Synonyms: (T-4)-bis(dibutylcarbamodithioato-κS,κS')zinc
  6. Drug

    Tolmetin

    go.drugbank.com/drugs/DB00500
    Approved

    A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid, 1-Methyl-5-p-toluoylpyrrole-2-acetic acid
  7. Drug

    Lucanthone

    go.drugbank.com/drugs/DB04967
    Investigational

    (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.

    Categories: Heterocyclic Compounds, 3-RingSynonyms: 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one, 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one
  8. Drug

    Bersacapavir

    go.drugbank.com/drugs/DB19035
    Investigational

    Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesSynonyms: N-(3-cyano-4-fluorophenyl)-1-methyl-4-(((2s)-1,1,1-trifluoro-2-propanyl)sulfamoyl)-1hpyrrole-2-carboxamide, 1h-pyrrole-2-carboxamide, n-(3-cyano-4-fluorophenyl)-1-methyl-4-((((1s)-2,2,2-trifluoro-1-methylethyl)amino)sulfonyl)-
  9. Drug

    Coumarin 120

    go.drugbank.com/drugs/DB08168
    Experimental

    Synonyms: 7-Amino-4-methylcoumarinCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  10. Drug

    Acedoben

    go.drugbank.com/drugs/DB04500
    Experimental

    Synonyms: N-Acetyl-PABA, N-Acetyl-p-aminobenzoic acid