Search
Dalteparin
go.drugbank.com/drugs/DB06779ApprovedInvestigationalDalteparin can also be safely used in most pregnant women. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. … It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000.
Products: FRAGMIN 2500 U.I/ML (ANTI-XA) VIAL DE 4 ML, FRAGMIN DAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalEndogenous Factor VIII is essential to the clotting process in the body due to its involvement in the clotting cascade where it is responsible for acting as a co-factor to Factor IX. … in the 1980s and 1990s [A31551, A32272].
Mixtures: VONCENTO 1000 UI/ 2400 UI, IMMUNATE 500 IU/375 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADETProducts: KOATE-DVI FOR INJECTION 250 iu/5 ml, KOATE-DVI FOR INJECTION 500 iu/5 mlGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalIt is approved by the FDA to treat advanced ovarian cancer in combination with [carboplatin], metastatic breast cancer in combination with [paclitaxel], non-small cell lung cancer in combination with [ … [L32950] It is also being investigated in other cancer and tumour types.
Products: GEMCITABINA MYLAN GENERICS, GEMCITABINA DR. REDDY'SFatty Acid Elongation in Mitochondria
smpdb.ca/view/SMP0000054MetabolicIn liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required. … Mitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation.
Pentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. … It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Products: DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial, DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mgIndium In-111 pentetate Drug Metabolism
smpdb.ca/view/SMP0130595MetabolicIndium In-111 pentetate passes through the liver and is then excreted from the body mainly through the kidney. … Indium In-111 pentetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Indium In-111 pentetateBleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalA complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Products: DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial, DBL™ BLEOMYCIN SULFATE FOR INJECTION 15 unitsBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalMoreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base. … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Mixtures: Difflam mouth gel, DIFFLAM MOUTH GELProducts: Biramine 3 mg/ml Spray zur Anwendung in der Mundhöhle, Lösung, Med-angin 3 mg/ml Spray zur Anwendung in der Mundhöhle, LösungSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalregulation in both children and adults. … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im Sc, Nutropin - Kit Pws(10mg) & Liq(10ml) Im ScProducts: OMNITROPE® SOLUCION INYECTABLE EN CARTUCHO DE 10 MG / 1.5 ML, NORDITROPIN 4 UIIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024.[L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.
Categories: Topoisomerase I InhibitorsProducts: CLORHIDRATO DE IRINOTECAN TRIHIDRATO 20 MG/ML, IRINOTECAN MYLAN GENERICS