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Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalIn HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] and [DB08934], Eplusa ([DB08934], [DB11613]), Harvoni ([DB08934], [DB09027]), [DB06290] and [DB08934 … Ribavirin is added to decrease relapse rates by accelerating viral clearance early in the treatment course [A19645].
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)Categories: Nucleosides and Nucleotides, Nucleic Acids, Nucleotides, and NucleosidesBlisters
go.drugbank.com/conditions/DBCOND0057795Synonyms: Blister of skin AND/OR mucosa, Blister of skin AND/OR mucosa (disorder)Levoketoconazole
go.drugbank.com/drugs/DB05667Approvedchanges in body composition, neuropsychiatric effects, changes in blood pressure and chemistry, and opportunistic infections. … [A244083, A29319, L39573] Levoketoconazole was approved by the FDA on December 30, 2021, and is currently marketed under the registered trademark RECORLEV by Xeris Pharmaceuticals, Inc.[L39563]
Categories: Sex Hormones and InsulinsCetalkonium
go.drugbank.com/drugs/DB11583ApprovedWithdrawn[A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. … Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations.
Mixtures: Oral Aid Kid Gel, Oral Aid Soothing GelCategories: Compounds used in a research, industrial, or household settingRomidepsin
go.drugbank.com/drugs/DB06176ApprovedInvestigationalRomidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDeep vein thrombophlebitis
go.drugbank.com/conditions/DBCOND0095181Drugs: EnoxaparinSynonyms: Venous phlebitis and thrombophlebitis deep, Acute embolism and thrombosis of unspecified deep veins of lower extremityGestational Diabetes Mellitus (GDM)
go.drugbank.com/conditions/DBCOND0043991Synonyms: Diabetes mellitus arising in pregnancyRolapitant
go.drugbank.com/drugs/DB09291ApprovedInvestigationalBy blocking Substance P from interacting with NK-1 receptors in the gut and the central nervous system, rolapitant prevents late-phase CINV. … Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and
Categories: Antiemetics and Antinauseants, Alimentary Tract and MetabolismTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[A225386] Comirnaty was granted a EUA in the UK on December 2, 2020,[L26676] and in Canada on December 9, 2020[L26671] for active immunization against SARS-CoV-2. … [L15027] On December 11, 2020, the FDA issued an Emergency Use Authorization (EUA) based on 95% efficacy in clinical trials and a similar safety profile to other viral vaccines over a span of approximately
Categories: Amino Acids, Peptides, and ProteinsMultifunctional protein CAD
go.drugbank.com/bio_entities/BE0002227TargetEnzymeHumansThe CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl … ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate. In the last step, DHOase catalyzes the cyclization of carbamoyl aspartate to dihydroorotate
Polypeptides: Multifunctional protein CAD