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Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedP188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217].
Botulinum toxin type B
go.drugbank.com/drugs/DB00042ApprovedNeurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex.
Biperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnIt has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Prilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit)Fluoride ion
go.drugbank.com/drugs/DB11257ApprovedInvestigationalFluoride ions are found in various minerals but are only present in trace amounts in water.
Metoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigational[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922]
YSIL6
go.drugbank.com/drugs/DB05017ExperimentalThe molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration.
Aflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigationalthe FDA as treatments for retinal diseases; Enzeevi (aflibercept-abzv)[L53053], approved in August 2024, was also approved by the FDA for similar indications. … [L47915] All five putative N-glycosylation sites on each polypeptide chain predicted by the primary sequence can be occupied with carbohydrates and exhibit some degree of chain heterogeneity, including
Dactylis glomerata pollen
go.drugbank.com/drugs/DB10379ApprovedDactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.
Mixtures: K-O-T Standardized Grass Pollen Mix, K-O-T Standardized Grass Pollen MixLolium perenne pollen
go.drugbank.com/drugs/DB10389ApprovedLolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.