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Telisotuzumab vedotin
go.drugbank.com/drugs/DB15104ApprovedInvestigational[L53193] Telizotuzumab vedotin-tllv was approved by the US FDA in May 2025 for previously treated advanced NSCLC patients with high c-Met protein overexpression,[L53158,L53183] becoming the first treatment … [L53158] The c-Met protein is found to be overexpressed in approximately 25% of advanced EGFR wild type, non-squamous NSCLC patients and is associated with poor prognosis and limited treatment options.
Categories: Amino Acids, Peptides, and ProteinsEthinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigationalEthinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability. … [A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.
Mixtures: Alisma 2mg/35µg Filmtabletten, ADELLA MINI TABLETA CON RECUBRIMIENTO DE GELATINACategories: Hormones and Related Agents, dienogest and ethinylestradiolResorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalIt is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses … It exerts a keratolytic activity. Resorcinol works by helping to remove hard, scaly, or roughened skin.
Mixtures: Up and up vagicaine, BENZOCAINE and RESORCINOLBlisters
go.drugbank.com/conditions/DBCOND0057795Synonyms: Blister of skin AND/OR mucosa, Blister of skin AND/OR mucosa (disorder)Idoxuridine
go.drugbank.com/drugs/DB00249ApprovedWithdrawnAn analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleosides and Nucleotides Excl. Reverse Transcriptase InhibitorsRomidepsin
go.drugbank.com/drugs/DB06176ApprovedInvestigationalRomidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigational[L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy. … In its statement, the FDA has mentioned that increased risk of venous thromboembolism with oral contraceptives such as drospirenone exists but remains lower than the risk of this condition during pregnancy
Mixtures: Drospirenone and Ethinyl Estradiol, Drospirenone and Ethinyl EstradiolCategories: drospirenone and estetrol, drospirenone and estrogenDeep vein thrombophlebitis
go.drugbank.com/conditions/DBCOND0095181Drugs: EnoxaparinSynonyms: Venous phlebitis and thrombophlebitis deep, Acute embolism and thrombosis of unspecified deep veins of lower extremityGestational Diabetes Mellitus (GDM)
go.drugbank.com/conditions/DBCOND0043991Synonyms: Diabetes mellitus arising in pregnancyMultifunctional protein CAD
go.drugbank.com/bio_entities/BE0002227TargetEnzymeHumansThe CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl … ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate. In the last step, DHOase catalyzes the cyclization of carbamoyl aspartate to dihydroorotate
Polypeptides: Multifunctional protein CAD