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Rutin
go.drugbank.com/drugs/DB01698ApprovedInvestigationalA flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Mixtures: Nutriforte Non-Acidic Vitamin C 1000 mg with Bioflavonoids, KORDEL`S C TIME ACID FREE C 1000MG TABLETCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersMethyclothiazide
go.drugbank.com/drugs/DB00232ApprovedWithdrawnA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Categories: Heterocyclic Compounds, 2-Ring, Genito Urinary System and Sex HormonesProducts: Duretic 5mgMK-886
go.drugbank.com/drugs/DB16739ExperimentalMK-886 is an experimental inhibitor of leukotriene synthesis.
Categories: Heterocyclic Compounds, 2-RingMK-4965
go.drugbank.com/drugs/DB08460ExperimentalMK-4965 is an HIV-1 reverse transcriptase inhibitor.
Categories: Heterocyclic Compounds, 1-RingmRNA-1345
go.drugbank.com/drugs/DB18739ApprovedInvestigationalmRESVIA was first approved in the EU and US in 2024 for use in patients 60 years of age and older. … mRNA-1345 is a nucleoside modified mRNA encoding the F-glycoprotein from RSV subtype A stabilized in its prefusion conformation.[L53393] It is the primary ingredient of the RSV vaccine mRESVIA.
Synonyms: Respiratory syncytial virus pre-fusion glycoprotein F mRNAVerubecestat
go.drugbank.com/drugs/DB12285InvestigationalIn the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of … Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor.
Categories: Heterocyclic Compounds, 1-RingHalofantrine
go.drugbank.com/drugs/DB01218ApprovedWithdrawnIt appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in the parasite being poisoned by its own waste.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesOnvitrelin ucalontide
go.drugbank.com/drugs/DB19183InvestigationalOnvitrelin ucalontide is under investigation in clinical trial NCT01485848 (EP-100 Plus Paclitaxel Versus Paclitaxel Alone in Patients With Ovarian Cancer).
Synonyms: Ep-100 (peptide), Ep-100 (conjugate of luteinizing hormone-releasing hormone with a cationic .alpha.-helical peptide for therapy of lhrh-expressing tumors)Benzphetamine
go.drugbank.com/drugs/DB00865ApprovedIllicitA sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (S)-(+)-N-benzyl-N,α-dimethylphenethylamine, d-N-methyl-N-benzyl-β-phenylisopropylamineNitroarginine
go.drugbank.com/drugs/DB04223Investigational(Neurochem Res 1995:200(4):451-6)
Synonyms: N(gamma)-nitro-L-arginine, L-NNA