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Integrin alpha-5
go.drugbank.com/bio_entities/BE0008988TargetHumansIntegrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.
Polypeptides: Integrin alpha-5Synonyms: VLA-5Thyroxine 5-deiodinase
go.drugbank.com/bio_entities/BE0009333TargetEnzymeHumansT1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710 … Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-
Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activityPseudouridine-5'-phosphatase
go.drugbank.com/bio_entities/BE0014361EnzymeHumansDephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine
Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphataseNADPH oxidase 5
go.drugbank.com/bio_entities/BE0018640TargetHumansCalcium-dependent NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed:12686516). Also synthesizes NAADP from its reduced NAADPH form which promotes Ca(2+) signaling...
Polypeptides: NADPH oxidase 5Camphor 5-monooxygenase
go.drugbank.com/bio_entities/BE0001246TargetPseudomonas putidaInvolved in a camphor oxidation system.
Polypeptides: Camphor 5-monooxygenaseFunction: camphor 5-monooxygenase activityPanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent. … Panitumumab was granted FDA approval on 27 September 2006.[L17663]
Products: VECTIBIX 20 MG/ML 5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET, VECTIBIX® 20 MG/ MLEthiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivityProducts: LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 ML, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 10 MLDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigationalDolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLETCategories: Antivirals used in combination for the treatment of HIV infections, MATE 1 InhibitorsOctreotide
go.drugbank.com/drugs/DB00104ApprovedInvestigational[L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. … Acromegaly is a life-threatening disease requiring life-long management.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SANDOSTATIN VIALES PARA DOSIS MULTIPLE 1 MG/ 5 ML, Sandostatin 1000 Mikrogramm/5 ml Injektions-/InfusionslösungSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OBESTOPPOR 5 MG CAPSULAS, SINHABIT 15 MG