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Satralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigational[eculizumab] in June 2019 and [inebilizumab] in June 2020). … Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive patients with NMOSD.
Synonyms: Humanised anti-IL-6 receptor monoclonal antibodyProducts: ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML, ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringeDupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt is also being studied in combination with another antibody that which targets IL-33.[L7225] … [L41900] It is used as monotherapy or in combination with other drugs, such as corticosteroids.
Products: Dupixent 300 mg Solution for Injection in Pre-filled Syringe, Dupixent 200mg Solution for Injection in Pre-Filled SyringeLiraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigational[A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor. … [A6932] Liraglutide was granted FDA approval on January 25, 2010.[L6070]
Categories: Drugs Used in DiabetesSynonyms: Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37], N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptideProtamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalSince it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps … Regardless, protamine sulfate continues to see contemporary use given its genuine effectiveness in reversing heparin effects.
Products: Protamine Sulfate Inj 10mg/ml USP, PROLFAT 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADETInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalInterferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Synonyms: IFN alpha-2B, r-INF-alphaMixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Ceftizoxime
go.drugbank.com/drugs/DB01332ApprovedWithdrawnIt has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
Products: CEFİZOX 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET, CEFIZOX 500 MG IM/IV ENJEKSİYON ICIN TOZ ICEREN FLAKON, 1 ADETMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThe pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue … [A221048, A221053, A221058, A221063, A221068, L16518] Mepolizumab is a fully-humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/MLCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigationalCarboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Synonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)Categories: Compounds used in a research, industrial, or household settingSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.
Mixtures: SULPERAZON 1G IM/IV, UNASYN IM/IV 1.5GProducts: B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 5 ADET, B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 100 ADETOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229108,A229113] It is estimated that labor induction with oxytocin is used in almost 10% of deliveries globally. … [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning.
Products: Oxyla 10 IU/mL Injection, Oxytocin Inj 10unit/ml USP