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Displaying results 2591 - 2600 of 10000 in total
  1. Target

    Trafficking protein particle complex subunit 6B

    go.drugbank.com/bio_entities/BE0004276
    TargetHumans

    Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797).

    Polypeptides: Trafficking protein particle complex subunit 6BSynonyms: TRAPP complex subunit 6B
  2. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites … The NSL complex also acts as a regulator of gene expression in mitochondria (PubMed:27768893).

    Polypeptides: KAT8 regulatory NSL complex subunit 3Synonyms: SI1, NSL complex protein NSL3
  3. Drug

    Fluorocholine F-18

    go.drugbank.com/drugs/DB15887
    Investigational

    Products: IASOcholine 1 GBq/ml - Injektionslösung, Fluorochol 222 MBq/ml Injektionslösung
  4. Drug

    Interferon alfacon-1

    go.drugbank.com/drugs/DB00069
    ApprovedWithdrawn

    Interferon alfacon-1 is produced in Escherichia coli (E. coli) cells that have been genetically altered by insertion of a synthetically constructed sequence that codes for Interferon alfacon-1. … Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions.

  5. Drug

    Foslevodopa

    go.drugbank.com/drugs/DB16683
    Approved

    Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants

    Mixtures: Produodopa 240 mg/ml + 12 mg/ml Infusionslösung
  6. Drug

    Pyrethrum extract

    go.drugbank.com/drugs/DB11087
    Approved

    The active compound is absorbed by the lice and destroys them by acting on their nervous systems but is thought to exert minimal effect on humans.

    Mixtures: Lice Enz Aer Shp, El piojito Lice KillingCategories: Compounds used in a research, industrial, or household setting
  7. Target

    Baculoviral IAP repeat-containing protein 1

    go.drugbank.com/bio_entities/BE0010810
    TargetHumans

    Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...

    Polypeptides: Baculoviral IAP repeat-containing protein 1
  8. Drug

    N-acetyltyrosine

    go.drugbank.com/drugs/DB11102
    ApprovedInvestigational

    N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group. … N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine [A32652].

    Mixtures: Aminosyn II 8.5% M In 20% Dextrose (dual Chamber), Aminosyn II 7% M In 10% Dextrose(dual Chamber)Synonyms: N-acetyltyrosin, N-acetyltyrosine
  9. Drug

    Pegaptanib

    go.drugbank.com/drugs/DB04895
    ApprovedWithdrawn

    Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.

  10. Drug

    Adenine

    go.drugbank.com/drugs/DB00173
    ApprovedInvestigationalNutraceutical

    A purine base and a fundamental unit of adenine nucleotides.

    Mixtures: HEPATAMINE %8 500 ML(SETLI), HEPATAMINE %8 500 ML(SETSIZ)