Search

Displaying results 2591 - 2600 of 10000 in total
  1. Drug

    ME-344

    go.drugbank.com/drugs/DB13062
    Investigational

    ME-344 has been used in trials studying the treatment of Solid Tumors.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    IBIO-100

    go.drugbank.com/drugs/DB18233
    Experimental

    IBIO-100 is a high molecular weight multimer of E3-Fc, an endostatin C-terminus and IgG1-Fc fusion protein.

  3. Drug

    Ethyl biscoumacetate

    go.drugbank.com/drugs/DB08794
    ApprovedWithdrawn

    Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: Ethyl bis(4-hydroxy-2-oxo-2h-1-benzopyran-3-yl)acetate
  4. Pathway

    Argininosuccinic Aciduria

    smpdb.ca/view/SMP0125766
    Disease

    Argininosuccinic Aciduria, (Argininosuccinase Deficiency, Argininosuccinate Lyase Deficiency, ASL Deficiency) is an autosomal recessive disorder caused by a mutation in the ASL gene which codes for argininosuccinate lyase. It results in ...

    Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 more
    Enzymes: Y+L amino acid transporter 1
  5. Drug

    Vusolimogene oderparepvec

    go.drugbank.com/drugs/DB23008
    ApprovedInvestigational

    [L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its … killing and GM-CSF promoting dendritic cell and monocyte activation to drive an anti-tumor immune response.

    Synonyms: Hsv-1 oncolytic viral strain rp1
  6. Drug

    Racivir

    go.drugbank.com/drugs/DB12753
    Investigational

    Racivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Jaktinib

    go.drugbank.com/drugs/DB17545
    Investigational

    Jaktinib is under investigation in clinical trial NCT04866056 (Jaktinib and Azacitidine in Treating Patients With MDS With MF or MDS/MPN With MF.). … Jaktinib is a JAK 1, JAK 2 and JAK 3 inhibitor, being developed by Suzhou Zelgen Biopharmaceuticals.

  8. Drug

    MK-0731

    go.drugbank.com/drugs/DB08037
    Investigational

    MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Thiamylal

    go.drugbank.com/drugs/DB01154
    ApprovedVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p919) … A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid, dihydro-5-(1-methylbutyl)-5-(2-propenyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione
  10. Drug

    Shark liver oil

    go.drugbank.com/drugs/DB11088
    Approved

    Shark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight. … Shark oil is a rich source of alkylglycerols and squalene, with relatively low amounts of n-3 polyunsaturated fatty acids.

    Mixtures: DG Health Hemorrhoidal, Rx Act Hemorrhoidal