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Trilaciclib
go.drugbank.com/drugs/DB15442ApprovedInvestigational[A229313] Trilaciclib was granted FDA approval on 12 February 2021.[L31823]
Artemether
go.drugbank.com/drugs/DB06697ApprovedInvestigationalArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy.
Masoprocol
go.drugbank.com/drugs/DB00179InvestigationalIt also serves as an antioxidant in fats and oils. [PubChem]
Fusarium oxysporum vasinfectum
go.drugbank.com/drugs/DB10435ApprovedFusarium oxysporum vasinfectum is a fungus which can provoke allergic reactions. Fusarium oxysporum vasinfectum extract is used in allergenic testing.
Ponesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079] Ponesimod was granted FDA approval on 18 March 2021.[L32709]
Benzgalantamine
go.drugbank.com/drugs/DB19353ApprovedInvestigational[L51564] Benzgalantamine was approved by the FDA in July 2024 for the treatment of mild-to-moderate dementia in Alzheimer's patients.[L51534,L51564]
Procaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedProcaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Disulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol.
Enfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalEnfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake. The first agent in the novel class...
Lurbinectedin
go.drugbank.com/drugs/DB12674ApprovedInvestigational[A214331] On June 15, 2020, the FDA granted accelerated approval and orphan drug designation to lurbinectedin for the treatment of adult patients with metastatic SCLC who have experienced disease progression … [A214310] It is a derivative of the marine-derived agent ecteinascidin ([trabectedin]), an anticancer agent found in extracts of the tunicate _Ecteinascidia turbinata_, with the primary difference being