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Elinzanetant
go.drugbank.com/drugs/DB18968ApprovedInvestigationalElinzanetant is a non-hormonal, selective, dual neurokinin 1 (NK-1) and 3 (NK-3) receptor antagonist. … [A274198] On July 23, 2025, it was approved by Health Canada to treat moderate to severe vasomotor symptoms (VMS) associated with menopause.
Categories: Neurokinin 1 Antagonists, Heterocyclic Compounds, 1-RingSynonyms: Benzamide, 3-(5-methyl-2-tbenzeneacetamide, n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha.,.alpha., 2-(3,5-bis(trifluoromethyl)phenyl)-n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-7-(hydroxymethyl)hexahydropyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,2-dimethylpropanamideCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalCandesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents … It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
Mixtures: CANDAM® 10/16 MG TABLETAS, CANDAM® 10/16 MG TABLETASCategories: Heterocyclic Compounds, 1-Ring, Angiotensin 2 Receptor BlockerOfatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigational[L12612] Although it has a similar molecular mechanism of action as [rituximab], another CD-20 monoclonal antibody used in the treatment of rheumatoid arthritis and B-cell non-Hodgkin's lymphoma, ofatumumab … [L12753] The FDA subsequently approved ofatumumab for the treatment of RMS on August 20, 2020.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: Jemvy 20 mg/0,4 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, JEMVY 20 MG/0,4 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalIt was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979. … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DEPO-TESTOSTERONE STERILE SOLUTION 100 mg/ml, DEPO-TESTOSTERONE STERILE SOLUTION 200 mg/mlInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalInsulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … Marketed as the brand name product Humalog, insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration.
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Pemetrexed Zentiva 10 mg/ml Infusionslösung, ALIMTA INFUZYON COZELTISI ICIN TOZ ICEREN FLAKON 10 ML, 1 ADETAceclofenac
go.drugbank.com/drugs/DB06736ApprovedIt is a more commonly prescribed drug in Europe. … It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670].
Mixtures: ZERODOL PCategories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs), Cytochrome P-450 SubstratesCalfactant
go.drugbank.com/drugs/DB06415ApprovedInvestigationalEach milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg of proteins including surfactant-associated … proteins B and C.
Synonyms: SF-RI 1Products: ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET, BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal InstillationToyocamycin
go.drugbank.com/drugs/DB13916Experimental4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. … It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Synonyms: 4-amino-5-cyano-7-(D-ribofuranosyl)-7H-pyrrolo(2,3-d)pyrimidine, 7-deaza-7-cyanoadenosineNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalA narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriol