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Veglin
go.drugbank.com/drugs/DB05890ExperimentalVEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma
Synonyms: VEGF-ASDNL343
go.drugbank.com/drugs/DB18678InvestigationalDNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
Quinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalIt was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
Seletracetam
go.drugbank.com/drugs/DB05885InvestigationalAs of 2010, its production was further halted due to the investigation of a newer antiepileptic agent, brivaracetam. … Food and Drug Administration (FDA) investigated as treatment of epilepsy and partial epilepsy however its development had been put on hold in July 2007.
Floxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalFloxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution.
EDP1815
go.drugbank.com/drugs/DB16486Investigationalinvestigated in several clinical trials (NCT05066373, NCT05439941, NCT05682222, NCT03733353, NCT04603027, NCT04488575, NCT05121480, NCT04393246) to evaluate its safety and efficacy in conditions such as
MDX-1303
go.drugbank.com/drugs/DB05945Investigationalfully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins known as
N4-Hydroxycytidine
go.drugbank.com/drugs/DB15660Experimental[A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells. … [A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage.
Bictegravir
go.drugbank.com/drugs/DB11799ApprovedInvestigationalBictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Solriamfetol
go.drugbank.com/drugs/DB14754ApprovedInvestigationalSolriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive ...