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Fenbendazole
go.drugbank.com/drugs/DB11410InvestigationalVet approvedFenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, ae...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesOrbifloxacin
go.drugbank.com/drugs/DB11443ExperimentalVet approvedOrbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSelamectin
go.drugbank.com/drugs/DB11459ExperimentalVet approvedSelamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in dogs as well as prevent heartworms, fleas, ear ...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDexamethasone isonicotinate
go.drugbank.com/drugs/DB11487ExperimentalVet approvedDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesMelengestrol
go.drugbank.com/drugs/DB11529ExperimentalVet approvedMelengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTetanus immune globulin, human
go.drugbank.com/drugs/DB11604ApprovedInvestigationalTetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Products: GAMMA TET P, TETAGAM PTocofersolan
go.drugbank.com/drugs/DB11635ApprovedD-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNomegestrol
go.drugbank.com/drugs/DB11636ApprovedNomegestrol is an ingredient in the EMA-authorised product Zoely.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVoclosporin
go.drugbank.com/drugs/DB11693ApprovedInvestigationalLupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesRacecadotril
go.drugbank.com/drugs/DB11696InvestigationalRacecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
Categories: N-substituted Glycines