Search

Displaying results 2631 - 2640 of 3599 in total

Drug
Chlordiazepoxide
go.drugbank.com/drugs/DB00475
ApprovedIllicit
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Dicloxacillin
go.drugbank.com/drugs/DB00485
ApprovedInvestigationalVet approved
One of the penicillins which is resistant to penicillinase.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
Drug
Pefloxacin
go.drugbank.com/drugs/DB00487
Approved
A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Zidovudine
go.drugbank.com/drugs/DB00495
ApprovedInvestigational
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid c...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
Drug
Darifenacin
go.drugbank.com/drugs/DB00496
ApprovedInvestigational
It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
Drug
Oxycodone
go.drugbank.com/drugs/DB00497
ApprovedIllicitInvestigational
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to seve...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Ritonavir
go.drugbank.com/drugs/DB00503
ApprovedInvestigational
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimen...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
Drug
Triflupromazine
go.drugbank.com/drugs/DB00508
ApprovedVet approved
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Categories: P-glycoprotein inhibitors, Dopamine D2 Receptor Antagonists
Drug
Alitretinoin
go.drugbank.com/drugs/DB00523
Approved
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess o...
Categories: P-glycoprotein substrates
Drug
Mephenytoin
go.drugbank.com/drugs/DB00532
ApprovedWithdrawn
Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates