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Displaying results 2631 - 2640 of 3888 in total
  1. Drug

    Nabiximols

    go.drugbank.com/drugs/DB14011
    Investigational

    neuropathic pain in adult patients with multiple sclerosis (MS) and as adjunctive analgesic treatment in adult patients with advanced cancer who experience moderate to severe pain during the highest tolerated dose

  2. Drug

    Verubecestat

    go.drugbank.com/drugs/DB12285
    Investigational

    In the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of

  3. Drug

    XL784

    go.drugbank.com/drugs/DB04991
    Investigational

    Results of single dose Phase I clinical trials of XL784 administered orally to 96 healthy volunteers have demonstrated that XL784 has attractive safety and pharmacokinetic profiles. … XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied metalloprotease inhibitors.

  4. Drug

    Elafin

    go.drugbank.com/drugs/DB05161
    Investigational

    The excellent tolerability of Elafin in human subjects was demonstrated in a Phase I clinical single dose escalating study.

  5. Drug

    Bemotrizinol

    go.drugbank.com/drugs/DB11206
    Approved

    Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity [A19212].

    Mixtures: Hansai Beestox Trial Kit Set Beestox Sun Cream
  6. Drug

    Esculin

    go.drugbank.com/drugs/DB13155
    Approved

    These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another group via a C-, S-,N-,O-, or Se- glycosidic bond.

  7. Drug

    Recombinant Bacterial ACE2 Receptors-like Enzyme

    go.drugbank.com/drugs/DB15741
    Investigational

    B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme whic...

  8. Drug

    Cyclothiazide

    go.drugbank.com/drugs/DB00606
    Approved

    As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibi...

    Categories: Genito Urinary System and Sex Hormones
  9. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic...

    Categories: Genito Urinary System and Sex Hormones
  10. Drug

    CYNK-001

    go.drugbank.com/drugs/DB15722
    Investigational

    CYNK-001 is a novel allogenic off-the-shelf natural killer (NK) cell therapy originating from human placental CD34+ hematopoietic stem cells and enriched with CD56+/CD3-.