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Karaya gum
go.drugbank.com/drugs/DB10535ApprovedKaraya gum allergenic extract is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household setting, Non-Standardized Food Allergenic ExtractPramlintide
go.drugbank.com/drugs/DB01278ApprovedInvestigationalIt is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Categories: Drugs Used in DiabetesDifenoxin
go.drugbank.com/drugs/DB01501ApprovedIllicitDifenoxin is an active metabolite of the anti-diarrheal drug, diphenoxylate, which is also used in combination with atropine in the brand mixture Lomotil(R). … it is still capable of crossing the blood brain barrier to produce weak sedative and analgesic effects.
Zorecimeran
go.drugbank.com/drugs/DB15843InvestigationalThe CVnCov Vaccine (or CV07050101) is in development by CureVac AG. … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body.
Velmanase alfa
go.drugbank.com/drugs/DB12374ApprovedInvestigationalof alpha-mannosidosis. … [A244509] As long-term enzyme replacement therapy, velmanase alfa supplements or restores the function of deficient alpha-mannosidase.
Zidesamtinib
go.drugbank.com/drugs/DB21623ApprovedInvestigational[L63808] The FDA approved zidesamtinib on July 22, 2026, for adults with locally advanced or metastatic ROS1-positive non-small cell lung cancer who received a prior ROS1 kinase inhibitor. … of resistance mutations, particularly the solvent front G2032R substitution, and progression of disease in the brain.
Ibalizumab
go.drugbank.com/drugs/DB12698ApprovedInvestigationalIbalizumab (also known as _ibalizumab-uiyk_ and formerly known as TNX-355) is a monoclonal antibody that binds to CD4 receptors on the surface of CD4-positive cells, preventing HIV particle entry into … This drug was approved in March 2018 for the management of treatment-resistant HIV [L1554].
Metocurine iodide
go.drugbank.com/drugs/DB00416ApprovedWithdrawnMetocurine Iodide is no longer available on the US market. … It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine
Argatroban
go.drugbank.com/drugs/DB00278ApprovedInvestigationalThe American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary … Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi.
Triflusal
go.drugbank.com/drugs/DB08814ApprovedWithdrawnThe benefits of this agent are the lack of action over the arachidonic acid pathway, the driven production of nitric oxide and the increase of cyclic nucleotide concentration on endothelial cells. … The latest translates into the expansion of peripheral blood vessels.[A31675] It is very important as a secondary prevention of ischemic stroke by offering a lower risk of bleeding.