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Eflepedocokin alfa
go.drugbank.com/drugs/DB16366Investigational[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).[L27666]
H3B-8800
go.drugbank.com/drugs/DB14017InvestigationalIt offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting [A32749
Cambinol
go.drugbank.com/drugs/DB15493ExperimentalThis activity is currently being investigated for its use as a cancer treatment.
Aluminium monostearate
go.drugbank.com/drugs/DB01375ExperimentalAlso known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics.
Colfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawnColfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. It was part of the first generation of commercially available artificial surfactants. It was developed by Burroughs Wel...
Centanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigationalreuptake inhibitor, positioning it as a new mechanistic option in a condition where response varies widely between individuals and many patients remain symptomatic on existing treatment. … [L63806,L63934] Established ADHD pharmacotherapy acts on norepinephrine and dopamine without a serotonergic component, and Otsuka describes centanafadine as the first and only approved norepinephrine-dopamine-serotonin
Isopropamide
go.drugbank.com/drugs/DB01625ApprovedVet approvedWithdrawnIsopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
Phylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigationalVitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin. Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X. It is indicated ...
Dimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigational[L32995] Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. … [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness.
Isavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalDue to low solubility in water of isavuconazole on its own, the isovuconazonium formulation is favorable as it has high solubility in water and allows for intravenous administration. … This formulation also avoids the use of a cyclodextrin vehicle for solubilization required for intravenous administration of other antifungals such as voriconazole and posaconazole, eliminating concerns