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Desoxycorticosterone pivalate
go.drugbank.com/drugs/DB01134ExperimentalVet approvedDesoxycorticosterone pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. It is white, odorless, and stable in air. It is practically insoluble in water, sparingly soluble in acetone, slightly soluble in methano...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Products: CEFRADUR 250 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 60 ML, CEFADROXILO SUSPENSION 125 MG / 5 MLDoxepin
go.drugbank.com/drugs/DB01142ApprovedInvestigationalDoxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: DOXEPIN AL 50, DOXEPIN AL 100Cefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Products: SEROL 250 MG/5 ML ORAL SÜSPANSIYON IÇIN TOZ ,60 ML, SEROL 250 MG/5 ML ORAL SÜSPANSIYON IÇIN TOZ ,100 MLDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigationalDesogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-bet...
Synonyms: 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-olCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Synonyms: p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid, 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersGefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalGefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is ma...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPiperacillin
go.drugbank.com/drugs/DB00319ApprovedInvestigationalSemisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Synonyms: (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: AUROTAZ-P 4.5 G, Aurotaz-P Powder for Injections 4.5 gDihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalA 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable s...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraene-4-carboxamideTolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnTolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline ...
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors