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Displaying results 2641 - 2650 of 10000 in total
  1. Drug

    Esketamine

    go.drugbank.com/drugs/DB11823
    ApprovedInvestigational

    [L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to

    Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone, L-ketamine
  2. Drug

    Azelastine

    go.drugbank.com/drugs/DB00972
    ApprovedInvestigational

    [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996. … allergic rhinitis in patients 6 years of age and older.

    Mixtures: DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 23 G, DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 6,4 GCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  3. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627]. … Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic.

    Mixtures: CEFTRIAXONA 1000 MG + SULBACTAM 500 MG, CEF-3 INJECTION IM (1G)Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
  4. Drug

    Fructose

    go.drugbank.com/drugs/DB04173
    ApprovedInvestigational

    Mixtures: Formula EmCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and

    Mixtures: Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung, Cosopt 20 mg/ml + 5 mg/ml AugentropfenCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  6. Drug

    Ginkgo biloba

    go.drugbank.com/drugs/DB01381
    ApprovedInvestigationalNutraceutical

    _Ginkgo biloba_ is found in a number of homeopathic and over-the-counter herbal products and dietary supplements, but it has no approved therapeutic indications by regulatory bodies, such as the FDA, EMA … It is originally native to China, and _ginkgo biloba_ extract has been used in traditional Chinese medicine for centuries.

    Mixtures: DOMINGO 5/10/80 MG EFERVESAN TABLET, 30 ADET, DOMINGO 5/10/80 MG EFERVESAN TABLET, 90 ADETCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP3A Inducers
  7. Drug

    Ornithine

    go.drugbank.com/drugs/DB00129
    ApprovedInvestigationalNutraceutical

    L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.

    Mixtures: AMINOPLASMAL-5% E INFUSION, NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 MLSynonyms: (S)-α,δ-diaminovaleric acid, L-Ornithine
  8. Drug

    Ciclopirox

    go.drugbank.com/drugs/DB01188
    ApprovedInvestigational

    Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.

    Mixtures: Ciclopirox 3% / Itraconazole 5% / Urea 20%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Interferon alfa-n1

    go.drugbank.com/drugs/DB00011
    ApprovedWithdrawn

    Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.

    Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsProducts: WELLFERON INYECTABLE 5 MU/ML, WELLFERON INYECTABLE 10 MU/ML.
  10. Drug

    Edoxaban

    go.drugbank.com/drugs/DB09075
    ApprovedInvestigational

    (PE) following 5-10 days of initial therapy with a parenteral anticoagulant. … It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: LIXIANA 15 MG FILM KAPLI TABLET ,10 TABLET, LIXIANA 15 MG