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Displaying results 2651 - 2660 of 10000 in total
  1. Drug

    4SC-203

    go.drugbank.com/drugs/DB12669
    Investigational

    4SC-203 has been used in trials studying the treatment of Acute Myeloid Leukemia.

  2. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards

    Synonyms: 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol, 2,4,4'-Trichloro-2'-hydroxydiphenyl etherMixtures: KURSEPT %19 + %1 KREM (30 G), IPATTON LOCION DESODORANTE Y SECANTE PARA PIES
  3. Target

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

    go.drugbank.com/bio_entities/BE0004551
    TargetHumans

    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly ...

    Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
  4. Drug

    G207

    go.drugbank.com/drugs/DB05827
    Investigational

    MediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans. … G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG.

    Synonyms: G 207, G-207
  5. Drug

    Dichloroacetic acid

    go.drugbank.com/drugs/DB08809
    ApprovedInvestigationalWithdrawn

    A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness. … DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization and removal of a wide variety of skin and tissue lesions), but was cancelled post market

    Products: Bichloracetic Acid 100%
  6. Target

    Transitional endoplasmic reticulum ATPase

    go.drugbank.com/bio_entities/BE0004572
    TargetHumans

    May more particularly play a role in caveolins sorting in cells (PubMed:21822278, PubMed:23335559). … May play a role in the ubiquitin-dependent sorting of membrane proteins to lysosomes where they undergo degradation (PubMed:21822278).

    Synonyms: 15S Mg(2+)-ATPase p97 subunit
  7. Indication

    Hepatitis C Infections

    go.drugbank.com/conditions/DBCOND0072126
    Drugs: Interferon alfa
    Synonyms: Hep non-A non-B, Hepatitis non-A non-B
  8. Drug

    VB-201

    go.drugbank.com/drugs/DB15259
    Investigational

    VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).

  9. Drug

    CN-201

    go.drugbank.com/drugs/DB18726
    Investigational

    CN-201 is a humanized anti-CD3/CD19 bispecific antibody.

  10. Drug

    Manganese cation

    go.drugbank.com/drugs/DB06757
    ApprovedInvestigationalNutraceutical

    Manganese is a transition metal that was first described in the 19th and 20th centuries. … [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor for proteins [A263657, A263662, A263667] making it an essential metal for normal development and

    Synonyms: MANGANESE(2+), MANGANESE ION(2+)Mixtures: TRACUTIL® 10 ML AMPOLLAS, Chela-chromium 200