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Tiludronic acid

[A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] … Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and [clodronic acid].

Colfosceril palmitate

Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. … [A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.

Simeprevir

Broad use of simeprevir occurred when it was used in combination with a newer drug, [DB08934]. … It is shown to display synergistic effects with interferon-α and HCV NS5B inhibitor, and additive effects with ribavirin in HCV replicon cells [A19629].

Marnetegragene autotemcel

Severe leukocyte adhesion deficiency-I (LAD-I) is a genetic disorder leading to frequent life-threatening infections and high fatality risks among affected pediatric patients. … [L56115, L56116] Marnetegragene autotemcel is indicated for pediatric patients with severe LAD-I lacking an available HLA-matched sibling donor.[L56115]

Oxtriphylline

It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. … Oxtriphylline is the choline salt form of [theophylline].

Oxiconazole

Oxiconazole is an antifungal agent that is commonly found in topical formulations. … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.

Molindone

An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. … It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors.

(+)-menthol

Odesivimab

INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320] … (i.e. through Fc-mediated immune effector function) antibody effects to play a role in combatting EBOV infection.

Eszopiclone

One major benefit of eszopiclone is that it is approved by the FDA for the long-term treatment of insomnia. … It is the active stereoisomer of zopiclone, belonging to the class of drugs known as _cyclopyrrolones_.