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Ripretinib
go.drugbank.com/drugs/DB14840ApprovedInvestigationalRipretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as [sunitinib] and [imatinib] … [L13769] It is the first drug approved as a fourth-line therapy in the specific setting of prior treatment with a minimum of 3 other kinase inhibitors.[L13778]
Florbetaben F-18
go.drugbank.com/drugs/DB09148ApprovedInvestigationalThis radioactive diagnostic drug is used for the non-invasive detection of the density of beta-amyloid plaques in the brain of adult patients with cognitive impairment.[A18514, L53703] … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain.
Synonyms: 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINEEquine Botulinum Neurotoxin A Immune FAB2
go.drugbank.com/drugs/DB13900ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in adults and pediatric patients. … Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A.
Etretinate
go.drugbank.com/drugs/DB00926ApprovedWithdrawnEtretinate was taken off the market in Canada in 1996 and America in 1998 due to the risk of birth defects. Etretinate is now used to treat T-cell lymphomas. … It is thought to bind to the retinoic acid receptors. Etretinate is also believed to enhance the binding of cAMP to the regulatory RI subunit of cAMP dependent protein kinases.
Categories: Antipsoriatics for Systemic Use, Retinoids for Treatment of PsoriasisMeclofenamic acid
go.drugbank.com/drugs/DB00939ApprovedInvestigationalVet approvedA non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Categories: Antiinflammatory Preparations, Non-Steroids for Topical Use, Topical Products for Joint and Muscular PainSynonyms: N-(2,6-dichloro-m-tolyl)anthranilic acid, N-(2,6-dichloro-3-methylphenyl)anthranilic acidrhThrombin
go.drugbank.com/drugs/DB04923ApprovedWithdrawnThe production of recombinant proteins is not dependent on the availability of blood from animals or human donors and can be scaled-up to meet market demand. … ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery.
Bifonazole
go.drugbank.com/drugs/DB04794ApprovedBifonazole is an azole antifungal drug.
Mixtures: . - Salbe + NagelsetCategories: Antifungals for Topical Use, Antifungals for Dermatological UseSulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnExcept for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.[L43942] … It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: N(1)-2-Thiazolylsulfanilamide, 4-Amino-N-2-thiazolylbenzenesulfonamideHuman interferon beta
go.drugbank.com/drugs/DB14999ApprovedInvestigationalIt is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity.[A191733,L12012] … [A191784] Interferon beta is currently being studied as a possible treatment for COVID-19, which results from infection with the novel 2019 SARS-CoV-2 virus.
Categories: Experimental Unapproved Treatments for COVID-19, Interferon Type IOcriplasmin
go.drugbank.com/drugs/DB08888ApprovedWithdrawnOcriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system.