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Displaying results 2661 - 2670 of 10000 in total
  1. Drug

    Methyltestosterone

    go.drugbank.com/drugs/DB06710
    ApprovedInvestigational

    Methyltestosterone is a schedule III drug in the US. … A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies.

  2. Drug

    Somapacitan

    go.drugbank.com/drugs/DB15093
    ApprovedInvestigational

    Somapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency. … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.

  3. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias. … [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications.

    Categories: Peroxisome Proliferator Receptor alpha Agonist, Peroxisome Proliferator-activated Receptor alpha AgonistsProducts: Nu-gemfibrozil Cap 300mg, Nu-gemfibrozil Tab 600mg
  4. Target

    Vitamin B12 transporter BtuB

    go.drugbank.com/bio_entities/BE0001470
    TargetTransporterEscherichia coli (strain K12)

    Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space (PubMed:4579869). It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

    Synonyms: Cobalamin receptor
  5. Target

    Neuropilin-1

    go.drugbank.com/bio_entities/BE0002129
    TargetHumans

    Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system.

    Synonyms: Vascular endothelial cell growth factor 165 receptor
  6. Target

    T-cell surface glycoprotein CD3 zeta chain

    go.drugbank.com/bio_entities/BE0003458
    TargetHumans

    When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z.

    Synonyms: T-cell receptor T3 zeta chain
  7. Target

    Neuropilin-2

    go.drugbank.com/bio_entities/BE0010030
    TargetHumans

    High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF

    Synonyms: Vascular endothelial cell growth factor 165 receptor 2
  8. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    drugs such as lenalidomide. … least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent.

  9. Drug

    Etacrynic acid

    go.drugbank.com/drugs/DB00903
    ApprovedInvestigational

    This compound has been classified as a loop or high ceiling diuretic. … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.

    Categories: Increased Diuresis at Loop of Henle
  10. Drug

    Potassium bitartrate

    go.drugbank.com/drugs/DB11107
    ApprovedInvestigational

    Potassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in Japan. … It is obtained as a byproduct of wine manufacture during the fermentation process.