Search

Displaying results 2671 - 2680 of 10000 in total
  1. Drug

    Methscopolamine

    go.drugbank.com/drugs/DB11315
    Approved

    The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications. … Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors.

    Mixtures: AlleRx-D, Allergy DN PE
  2. Target

    Nitric oxide synthase oxygenase

    go.drugbank.com/bio_entities/BE0001483
    TargetStaphylococcus aureus (strain MW2)

    Catalyzes the production of nitric oxide.

    Synonyms: SANOS
  3. Drug

    TOP-1288

    go.drugbank.com/drugs/DB14839
    Investigational

    TOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis

  4. Drug

    Estetrol

    go.drugbank.com/drugs/DB12235
    ApprovedInvestigational

    [L33184] On April 15 2021, Mayne Pharma Group Limited and Mithra Pharmaceuticals were granted FDA approval for the oral contraceptive Estelle/Nextstellis, a combination of [drospirenone] and estetrol … The combination of drospirenone and estetrol offers a new choice with a favourable safety profile for women seeking contraceptive therapy.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 15α-hydroxyestriol
  5. Drug

    Lorpiprazole

    go.drugbank.com/drugs/DB09195
    Approved

    Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder.[A31634] It is a piperazinyl-triazole derivative.[T83]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  6. Drug

    BG-777

    go.drugbank.com/drugs/DB05839
    Experimental

    BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.

  7. Drug

    Methyltestosterone

    go.drugbank.com/drugs/DB06710
    ApprovedInvestigational

    Methyltestosterone is a schedule III drug in the US. … A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Remoxipride

    go.drugbank.com/drugs/DB00409
    ApprovedWithdrawn

    Remoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors. … [A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512]

    Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 Substrates
  9. Drug

    Hyperforin

    go.drugbank.com/drugs/DB01892
    InvestigationalNutraceutical

    One of the most important members of this family, due to its medical properties, is _Hypericum perforatum_, also known as St John's wort. … Hyperforin is a phytochemical generated by the plants of the Hypericum family.

  10. Pathway

    Acylcarnitine (15Z)-tetracos-15-enoylcarnitine

    smpdb.ca/view/SMP0124424
    Metabolic

    (15Z)-tetracos-15-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (15Z)-tetracos-15-enoyl-CoA reacts with L-carnitine to form (15Z)-tetracos-15-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more