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Displaying results 2671 - 2680 of 10000 in total
  1. Drug

    Londamocitinib

    go.drugbank.com/drugs/DB19190
    Investigational

    Londamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high

    Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-
  2. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive

    Mixtures: Triplixam 10 mg/2,5 mg/5 mg Filmtabletten, Triplixam 5 mg/1,25 mg/10 mg FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  3. Drug

    Imatinib

    go.drugbank.com/drugs/DB00619
    ApprovedInvestigational

    Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … [A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr.

    Synonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  4. Drug

    Linagliptin

    go.drugbank.com/drugs/DB08882
    ApprovedInvestigational

    Linagliptin was approved by the FDA on May 2, 2011[L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050

    Synonyms: (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dioneMixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MG
  5. Drug

    Ustekinumab

    go.drugbank.com/drugs/DB05679
    ApprovedInvestigational

    Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. … [A187349] It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice.

    Categories: Interleukin-12 Antagonist, Interleukin-23 AntagonistProducts: STELARA® 90 MG/ML, Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL
  6. Drug

    Treprostinil palmitil

    go.drugbank.com/drugs/DB18792
    Investigational

    Synonyms: Acetic acid, 2-(((1r,2r,3as,9as)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3s)- 3-hydroxyoctyl)-1h-benz(f)inden-5-yl)oxy)-, hexadecyl ester, Hexadecyl 2-(((1r,2r,3as,9as)-2-hydroxy-1-((s)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1h-cyclopenta(b)naphthalen-5-yl)oxy)acetate
  7. Drug

    Fidrisertib

    go.drugbank.com/drugs/DB18064
    Investigational

    Synonyms: (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin-4-yl)piperazine-1-carboxylate, 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2-b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester
  8. Drug

    Gartisertib

    go.drugbank.com/drugs/DB18770
    Investigational

    Synonyms: 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(oxetan-3-yl)piperazin-1-yl)carbonyl)-1-piperidyl)-3-pyridyl)pyrazolo(1,5-a)pyrimidine-3-carboxamide, Pyrazolo(1,5-a)pyrimidine-3-carboxamide, 2-amino-6-fluoro-n-(5-fluoro-4-(4-((4-(3-oxetanyl)-1-piperazinyl)carbonyl)-1-piperidinyl)-3-pyridinyl)-
  9. Drug

    Ferrous fumarate

    go.drugbank.com/drugs/DB14491
    ApprovedInvestigational

    Used in treatment of iron deficiency anemia.

    Synonyms: Iron(2+) fumarateMixtures: Vitamin C 202,8 mg/0,8 mg/100 mg - Hartkapseln, FERROZINC KAPSUL, 20 ADET
  10. Drug

    Delolimogene mupadenorepvec

    go.drugbank.com/drugs/DB17326
    Investigational

    Synonyms: Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound isoleucine zipper-containing human cd40 ligand-specifying)