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Displaying results 2681 - 2690 of 8974 in total

Drug
Proparacaine
go.drugbank.com/drugs/DB00807
ApprovedVet approved
It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Drug
Cisapride
go.drugbank.com/drugs/DB00604
ApprovedWithdrawn
In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. … The FDA issued a warning letter regarding this risk to health care professionals and patients.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Drug
Dronabinol
go.drugbank.com/drugs/DB00470
ApprovedIllicitInvestigational
Due to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting … associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments [FDA Label].
Drug
Sugemalimab
go.drugbank.com/drugs/DB16641
ApprovedInvestigational
The antibody has also been granted the Breakthrough Therapy Designation by the FDA to treat relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) and an orphan drug designation … to treat T-cell lymphoma.
Drug
Tetrachlorodecaoxide
go.drugbank.com/drugs/DB05389
Approved
The trial is being conducted in Germany at the University of Heidelberg and the National Centre for Tumor Diseases. … The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the balance between inflammation and phagocytosis, a state in which the
Categories: Compounds used in a research, industrial, or household setting
Drug
Moclobemide
go.drugbank.com/drugs/DB01171
ApprovedInvestigational
A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Antidepressive Agents Indicated for Depression
Drug
Imlifidase
go.drugbank.com/drugs/DB15258
ApprovedInvestigational
[A225916] Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life. … to non-self HLA antigens, face additional barriers to transplantation.
Drug
Thalidomide
go.drugbank.com/drugs/DB01041
ApprovedInvestigationalWithdrawn
It has been reintroduced and used for a number of inflammatory disorders and cancers. … Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception
Drug
Iopromide
go.drugbank.com/drugs/DB09156
Approved
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. … [A260751] Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction
Categories: Compounds used in a research, industrial, or household setting
Drug
Papaverine
go.drugbank.com/drugs/DB01113
ApprovedInvestigational
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.
Categories: Drugs for Functional Gastrointestinal DisordersInternational brands: Ro-Papav