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Displaying results 2681 - 2690 of 2828 in total
  1. Target

    Proteasome subunit beta type-9

    go.drugbank.com/bio_entities/BE0004737
    TargetHumans

    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic

    Synonyms: Multicatalytic endopeptidase complex chain 7
  2. Drug

    Opipramol

    go.drugbank.com/drugs/DB12930
    Investigational

    Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

    Categories: Membrane Transport Modulators
  3. Drug

    Niguldipine

    go.drugbank.com/drugs/DB09239
    Experimental

    Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.

    Categories: Membrane Transport Modulators
  4. Drug

    Evocalcet

    go.drugbank.com/drugs/DB12388
    Investigational

    Evocalcet has been used in trials studying the treatment of Hyperparathyroidism and Secondary Hyperparathyroidism.

    Categories: Sex Hormones and Insulins
  5. Drug

    Policresulen

    go.drugbank.com/drugs/DB13492
    Investigational

    Categories: Genito Urinary System and Sex Hormones
  6. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymb...

    Categories: Membrane Transport Modulators
  7. Drug

    Caroverine

    go.drugbank.com/drugs/DB13835
    Investigational

    Categories: Membrane Transport Modulators
  8. Target

    Lysine-specific histone demethylase 1A

    go.drugbank.com/bio_entities/BE0010091
    TargetHumans

    Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development (PubMed:16079794, PubMed:16140033

    Synonyms: BRAF35-HDAC complex protein BHC110
  9. Drug

    Protamine sulfate

    go.drugbank.com/drugs/DB09141
    ApprovedInvestigational

    Regardless, protamine sulfate continues to see contemporary use given its genuine effectiveness in reversing heparin effects. … The agent elicits this heparin reversal predominantly via the formation of an inactive complex between the anionic nature of heparin and its own cationic state [A174778, A174781, L5371].

  10. Drug

    Dapivirine

    go.drugbank.com/drugs/DB08639
    Investigational

    Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.

    Categories: Genito Urinary System and Sex Hormones