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Sorbitol
go.drugbank.com/drugs/DB01638ApprovedInvestigationalSorbitol occurs naturally and is also produced synthetically from glucose. … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Mixtures: Cleanse Gut And Colon, INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion)Categories: Indicators and Reagents, Diet, Food, and NutritionAcetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978. … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it is the first monomeric ionic compound used as an X-ray contrast agent.
Pentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Mixtures: Pentazocine and naloxone, Pentazocine and naloxoneCategories: pentazocine and naloxoneTerpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnIt is derived from sources such as turpentine, oregano, thyme and eucalyptus. … It was popular in the United States since the late nineteenth century, but was removed from marketed medications in the 1990s after FDA stated that "based on evidence currently available, there are inadequate
Synonyms: Terpin cis-form hydrateArginine
go.drugbank.com/drugs/DB00125ApprovedInvestigationalNutraceuticalAn essential amino acid that is physiologically active in the L-form.
Mixtures: Aminosyn II and Dextrose, Aminosyn II and DextroseCategories: arginine and lysine, Blood and Blood Forming OrgansHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalneed for therapeutic monitoring, and serious side effects of secondary cancer and birth defects. … Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Categories: Antineoplastic and Immunomodulating AgentsFT516
go.drugbank.com/drugs/DB15732InvestigationalFT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC). … This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.
Benzthiazide
go.drugbank.com/drugs/DB00562ApprovedThey inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. … Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics).
Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsIoxitalamic acid
go.drugbank.com/drugs/DB13444ApprovedWithdrawn[A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. … Ioxitalamate is an ionic iodinated contrast medium.[A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.
Cenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigationalCenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures. … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.