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Iopromide
go.drugbank.com/drugs/DB09156ApprovedIopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. … [A260751] Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction
Categories: Compounds used in a research, industrial, or household settingSugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalThe antibody has also been granted the Breakthrough Therapy Designation by the FDA to treat relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) and an orphan drug designation … to treat T-cell lymphoma.
Moclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Antidepressive Agents Indicated for DepressionElvitegravir
go.drugbank.com/drugs/DB09101ApprovedInvestigationalOn September 24, 2014, the FDA approved the single pill form of elvitegravir. … Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. It was FDA approved on August 27, 2012.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTetrachlorodecaoxide
go.drugbank.com/drugs/DB05389ApprovedThe trial is being conducted in Germany at the University of Heidelberg and the National Centre for Tumor Diseases. … The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the balance between inflammation and phagocytosis, a state in which the
Categories: Compounds used in a research, industrial, or household settingBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Categories: Retinoids for cancer treatment, Compounds used in a research, industrial, or household settingNedaplatin
go.drugbank.com/drugs/DB13145ApprovedInvestigationalIt is less nephrotoxic than [DB00515] but has proven equally effective. It was approved for use in Japan in 1995.
Synonyms: (glycolato-O,O')diammineplatinum(II)Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. … The FDA issued a warning letter regarding this risk to health care professionals and patients.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeThalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers. … Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception
Imlifidase
go.drugbank.com/drugs/DB15258ApprovedInvestigational[A225916] Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life. … to non-self HLA antigens, face additional barriers to transplantation.