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Afamelanotide
go.drugbank.com/drugs/DB04931ApprovedAfamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). … [A187202,A187205] Afamelanotide is currently the only approved drug therapy used in the management of erythropoietic protoporphyria, having received approval in the EU in December 2014[L9119] and subsequent
Categories: Compounds used in a research, industrial, or household setting, Melanocortin 1 Receptor (MC1-R) AgonistsSynonyms: MT-I, Melanotan ILevacetylmethadol
go.drugbank.com/drugs/DB01227ApprovedWithdrawnLevacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. … Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased as well.[L44052,T862]
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate, 1-alpha-AcetylmethadolAdenylate cyclase
go.drugbank.com/bio_entities/BE0010179TargetHumansAdenylate cyclase that mediates formation of both cyclic AMP (cAMP) and cyclic di-AMP (c-di-AMP) (PubMed:11113152, PubMed:18541530, PubMed:23229509). … Also involved in inflammation by acting as a diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into c-di-AMP (By similarity).
Synonyms: Cyclic di-AMP synthase ADCY7Bronopol
go.drugbank.com/drugs/DB13960ApprovedL4873] and in other products where it may not primarily be used in the role of a non-medicinal preservative antimicrobial [L4874]. … Nevertheless, ongoing contemporary re-evaluations of bronopol use in large markets such as Canada now place various compositional and product restrictions on the use of the agent in cosmetic products [
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-nitropropane-1,3-diol, 2-Nitro-2-bromo-1,3-propanediolCapsicum oleoresin
go.drugbank.com/drugs/DB11131ApprovedCapsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. … Due to its analgesic properties, capsicum oleoresin is used to temporarily relieve of minor aches and pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied
Mixtures: DermacinRx Lexitral PharmaPak II, SLOAN`S ANALGESIC RUBSynonyms: Oleoresins of capsicumIndigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to aid in visualizing ureter integrity in cystoscopic assessments.[L42600] … This compound is an acid-base indicator and is used in the production of food colorants and pH tests.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingSynonyms: 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid, FD&C Blue #2Lactose
go.drugbank.com/drugs/DB04465ApprovedInvestigationalWithdrawnA disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
Mixtures: SERECOR® FORTE DPI 100, SYNTHROID® 112 MCG TABLETASCategories: Compounds used in a research, industrial, or household settingAminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Categories: Sensitizers Used in Photodynamic/radiation TherapySynonyms: 5-ALA, δ-ALAJoubert Syndrome
smpdb.ca/view/SMP0000582DiseaseThe symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. … Joubert syndrome is a condition in which brain development is not completed as it should be, including the lack or underdevelopment of the part of the brain that regulates balance and coordination and
Enzymes: Activating molecule in BECN1-regulated autophagy protein 1Joubert Syndrome
smpdb.ca/view/SMP0125809DiseaseThe symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. … Joubert syndrome is a condition in which brain development is not completed as it should be, including the lack or underdevelopment of the part of the brain that regulates balance and coordination and
Enzymes: Activating molecule in BECN1-regulated autophagy protein 1