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Displaying results 261 - 270 of 4626 in total
  1. Drug

    Tradipitant

    go.drugbank.com/drugs/DB12580
    ApprovedInvestigational

    Tradipitant is a selective, high-affinity antagonist at human substance P/neurokinin-1 (NK-1) receptors. … [A275353] Approved by the FDA on December 30, 2025, tradipitant is indicated for the prevention of vomiting induced by motion.

  2. Indication

    Prophylaxis of Venous thrombosis

    go.drugbank.com/conditions/DBCOND0022148
    Drugs: Acenocoumarol · Dextran · Heparin · Warfarin
  3. Drug

    Octisalate

    go.drugbank.com/drugs/DB11062
    Approved

    Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicyla...

    Mixtures: No-AD Quality Guaranteed SPF 15 Uva/uvb Sun Protection Lotion, Awaken by Quality Choice Long-Lasting Oil-Free Moisturizer Broad Spectrum SPF 15
  4. Indication

    Polyuria

    go.drugbank.com/conditions/DBCOND0001413
    Drugs: Amiloride · Desmopressin
    Synonyms: Urine output high
  5. Target

    Serine protease HTRA1

    go.drugbank.com/bio_entities/BE0017623
    TargetHumans

    Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteog...

    Synonyms: High-temperature requirement A serine peptidase 1
  6. Drug

    Ioxitalamic acid

    go.drugbank.com/drugs/DB13444
    ApprovedWithdrawn

    [A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995.

    Categories: Watersoluble, Nephrotropic, High Osmolar X-Ray Contrast Media
  7. Drug

    Eflornithine

    go.drugbank.com/drugs/DB06243
    ApprovedInvestigationalWithdrawn

    [A262823,L49318] Subsequently, on December 14, 2023, the FDA approved eflornithine again but under the brand name IWILFIN as an oral maintenance therapy to reduce the risk of relapse in adult and pediatric … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued

  8. Drug

    Tolevamer

    go.drugbank.com/drugs/DB01344
    Approved

    Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. … It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines.

  9. Drug

    Dextrothyroxine

    go.drugbank.com/drugs/DB00509
    ApprovedWithdrawn

    Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood.

  10. Drug

    Bempedoic acid

    go.drugbank.com/drugs/DB11936
    ApprovedInvestigational

    Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. … High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events.