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Fazpilodemab
go.drugbank.com/drugs/DB18924InvestigationalFazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis
Synonyms: immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chain, 410-valine], anti-(human β-Klotho protein) (human monoclonal HKLB4206 γ1-chain), disulfide with monoclonal HKLB4206 κ-chain, (229→225'),(232→228')-bis(disulfide) with immunoglobulin G1 [365-tryptophan] antSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[Somatrem] was the first available recombinant HGH and was largely replaced by somatropin, another form of recombinant HGH. … Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im Sc, Nutropin - Kit Pws(10mg) & Liq(10ml) Im ScCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsCarbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalSome adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and/or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. … of this ingredient as an oral wound healing agent [L1976].
Products: Ear Wax Removal Drops Up and Up, Foster and Thrive Earwax Removal DropsRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedIt occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.
Mixtures: B-2 100mg With C 20mg, B Complex 25mg Vitamin SupplementCategories: Enzymes and Coenzymes, Alimentary Tract and MetabolismMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalMitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_. … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix.
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsProducts: Mutamycin Inj 20mg/vial, ALPHAMYCINA® 20MG POLVO LIOFILIZADO PARA INYECCIÓNChlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: Chlordiazepoxide and Amitriptyline Hydrochloride, Chlordiazepoxide and Amitriptyline HClCategories: Hypnotics and Sedatives, Benzodiazepines and benzodiazepine derivativesGuanethidine
go.drugbank.com/drugs/DB01170ApprovedWithdrawnAn antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. … It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Categories: guanethidine and diuretics, Antiglaucoma Preparations and MioticsProducts: Ismelin 25mg, Guanethidine 10 Tab 10mgLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalLarotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays … an important role in tumor cell growth and survival.
Categories: Antineoplastic and Immunomodulating AgentsProducts: VITRAKVI HARD CAPSULE 25MG, VITRAKVI ORAL SOLUTION 20MG/MLGlycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: Up and Up Hemorrhoidal, ENDURA® UDCategories: Alimentary Tract and Metabolism, Basic Ointments and ProtectantsEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalAs the binding of esomeprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists … Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme
Synonyms: Omeprazole S-formMixtures: VIMOVO 500MG/20MG MODIFIED-RELEASE TABLETS, Naproxen and esomeprazole magnesium