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Etryptamine
go.drugbank.com/drugs/DB01546ApprovedIllicitWithdrawn1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawn[A39986] Rifamycin was further developed by Cosmo Technologies Ltd and approved in November 16, 2018 by the FDA as a prescription drug after being granted the designation of Qualified Infectious Disease
Products: RIFAMIN®Fostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigational[A215057] Fostemavir is the first attachment inhibitor to receive FDA approval, granted in July 2020 for use in combination with other antiretrovirals in highly treatment-experienced patients with multidrug-resistant
Belzutifan
go.drugbank.com/drugs/DB15463ApprovedInvestigationalBelzutifan received FDA approval for the treatment of select VHL-associated cancers on August 13, 2021.
Ormeloxifene
go.drugbank.com/drugs/DB13310ExperimentalOrmeloxifene is a third-generation selective estrogen receptor (ER) modulator.
PRO 2000
go.drugbank.com/drugs/DB05385InvestigationalPRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials.
International brands: Lavelin FABermekimab
go.drugbank.com/drugs/DB14947InvestigationalBermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Synonyms: RA-18C3CH-1504 L-isomer
go.drugbank.com/drugs/DB19052InvestigationalCH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Donislecel
go.drugbank.com/drugs/DB17961Approved[L47196] Donislecel was approved by the FDA on June 28, 2023, and is available under the brand name LANTIDRA from CellTrans Inc.[L47196]
Tezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigationalIt was granted FDA approval on December 17, 2021, and is currently marketed under the trademark TEZSPIRE by Amgen/AstraZeneca.