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Displaying results 2691 - 2700 of 10000 in total
  1. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]

    Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide
  2. Drug

    Lasmiditan

    go.drugbank.com/drugs/DB11732
    ApprovedInvestigational

    [A187316] Triptans abort migraines via action at several serotonin receptors, including 5-HT<sub>1D</sub> and 5-HT<sub>1B</sub> receptors, and activity at the 5-HT<sub>1B</sub> receptor has been specifically … [L9338,L9356] It was also approved by the European Commission on August 17, 2022.[L43997] Traditionally, the triptan class of anti-migraine medications (e.g.

    Categories: Serotonin (5-HT) 1F Receptor Agonists
  3. Drug

    Elismetrep

    go.drugbank.com/drugs/DB15287
    Investigational

    Elismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).

  4. Drug

    AMG-119

    go.drugbank.com/drugs/DB17363
    Investigational

    AMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811]

  5. Drug

    MK-7622

    go.drugbank.com/drugs/DB12897
    Investigational

    MK-7622 has been used in trials studying the treatment of Alzheimer's Disease.

  6. Drug

    Opicapone

    go.drugbank.com/drugs/DB11632
    ApprovedInvestigational

    [A36938, A203048] Many patients with Parkinson’s disease treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) experience motor complications over time, which calls for the management … [L13772] It is marketed under the brand name Ongentys as once-daily oral capsules.

  7. Drug

    MK-4830

    go.drugbank.com/drugs/DB17454
    Investigational

    MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT) 4 receptor.

  8. Drug

    WP-1122

    go.drugbank.com/drugs/DB17192
    Investigational

    WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361]

  9. Drug

    Turpentine

    go.drugbank.com/drugs/DB11120
    Approved

    It is used as a solvent and base material in organic synthesis reactions.

    Mixtures: BUĞUMENTOL BUĞU, 40 G, KATALJİN BUHARLAŞAN MERHEM, 40 G
  10. Drug

    Filgotinib

    go.drugbank.com/drugs/DB14845
    ApprovedInvestigational

    ], interleukin-6 (IL-6) blockers, and tumor necrosis factor (TNF) inhibitors. … [A189165] Non-selective JAK inhibitors like [tofacitinib] target JAK1 and JAK3 subtypes with minimal activity at JAK2. In contrast, the newly approved filgotinib is a highly selective JAK1 inhibitor.