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Displaying results 2691 - 2700 of 6196 in total
  1. Drug

    Thonzonium

    go.drugbank.com/drugs/DB09552
    Approved

    It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone. … It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication.

  2. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Soon afterward, it was shown that these protein nutrients were cleaved by pepsin to products called _peptones_ [A32603]. … Pepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing practice [L2363].

  3. Indication

    Neoplasms

    go.drugbank.com/conditions/DBCOND0027948
    Drugs: Betamethasone phosphate · Prednisolone phosphate
    Synonyms: CA - Cancer, Ca - unspecified site
  4. Drug

    Urokinase

    go.drugbank.com/drugs/DB00013
    ApprovedInvestigationalWithdrawn

    [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138] … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.

  5. Drug

    Light mineral oil

    go.drugbank.com/drugs/DB11579
    Approved

    Mixtures: QV FLARE UP BATH OIL, QV Flare Up Bath Oil
  6. Drug

    Mephentermine

    go.drugbank.com/drugs/DB01365
    ApprovedWithdrawn

    A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia. Although the central stimulant effects of mephentermine ...

  7. Drug

    Evinacumab

    go.drugbank.com/drugs/DB15354
    ApprovedInvestigational

    [L31838] In September and December 2023, evinacumab was also approved by Health Canada and EMA, respectively, for the same indication.[L49956,L49966]

  8. Drug

    RI 624

    go.drugbank.com/drugs/DB05892
    Experimental

    RI 624 is being developed by Rinat and is currently in Phase I clinical trials.

  9. Indication

    Muscle-invasive Bladder Cancer

    go.drugbank.com/conditions/DBCOND0042339
    Drugs: Atezolizumab · Durvalumab · Pembrolizumab
    Synonyms: Ca bladder, Bladder Ca
  10. Target

    Histone acetyltransferase KAT2B

    go.drugbank.com/bio_entities/BE0002683
    TargetHumans

    Functions as a histone acetyltransferase (HAT) to promote transcriptional activation (PubMed:8945521). Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles (PubMed:894...

    Synonyms: P/CAF