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Metabotropic glutamate receptor 5
go.drugbank.com/bio_entities/BE0001192TargetHumansG protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a...
Polypeptides: Metabotropic glutamate receptor 55-hydroxytryptamine receptor 5A
go.drugbank.com/bio_entities/BE0004688TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521).
Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: 5-HT-5, 5-HT5A5-hydroxytryptamine 2 receptor
go.drugbank.com/bio_entities/BE0004881TargetHumansPlays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).
Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A5-hydroxytryptamine receptor 2C
go.drugbank.com/bio_entities/BE0004882TargetRatG-protein coupled receptor for 5-hydroxytryptamine (serotonin).
Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: 5-HT1C, 5-HT-1C5-hydroxytryptamine receptor 2
go.drugbank.com/bio_entities/BE0004957TargetHumansPlays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).
Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2AChromobox protein homolog 5
go.drugbank.com/bio_entities/BE0009056TargetHumansComponent of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phospho...
Polypeptides: Chromobox protein homolog 5Serine repeat antigen 5
go.drugbank.com/bio_entities/BE0009196TargetPlasmodium falciparumPolypeptides: Serine repeat antigen 55-hydroxytryptamine receptor 3D
go.drugbank.com/bio_entities/BE0009585TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-DEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalTraditionally, warfarin, a vitamin K antagonist, was used for stroke prevention in these individuals but effective use of this drug is limited by it's delayed onset, narrow therapeutic window, need for … In addition to once daily dosing, the benefits over warfarin also include significant reductions in hemorrhagic stroke and GI bleeding, and improved compliance, which is beneficial as many patients will
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: LIXIANA 15 MG, LIXIANA FILM-COATED TABLET 15 MGOrnithine
go.drugbank.com/drugs/DB00129ApprovedInvestigationalNutraceuticalL-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine. … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine.
Synonyms: (S)-α,δ-diaminovaleric acid, L-OrnithineMixtures: AMINOPLASMAL-5% E INFUSION, NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML