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Displaying results 2701 - 2710 of 8009 in total
  1. Drug

    Penpulimab

    go.drugbank.com/drugs/DB16747
    ApprovedInvestigational

    [A273843,A273848] Penpulimab-kcqx was approved by the US FDA in April 2025 for the treatment of nasopharyngeal carcinoma in select patients.[L52993,L52998]

  2. Drug

    Benzthiazide

    go.drugbank.com/drugs/DB00562
    Approved

    Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. … Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity.

  3. Drug

    Valdecoxib

    go.drugbank.com/drugs/DB00580
    ApprovedWithdrawn

    Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.

  4. Drug

    Volanesorsen

    go.drugbank.com/drugs/DB15067
    Approved

    [L16621] This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high risk for pancreatitis, who have had inadequate response to triglyceride lowering therapy. … [L16621] Volanesorsen was granted a conditional approval by the European Medicines Agency.[L16621]

  5. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Mixtures: MYOGESIC-OR
  6. Drug

    Doconexent

    go.drugbank.com/drugs/DB03756
    ApprovedInvestigational

    It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae.

  7. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    for the management of neuropathic pain (although there is only minimal evidence of efficacy for this condition). … [A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years.

    Categories: Antidepressive Agents Indicated for Depression
  8. Drug

    Idecabtagene vicleucel

    go.drugbank.com/drugs/DB16665
    ApprovedInvestigational

    [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from a patient to express a CAR for a tumor specific antigen. … [L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA on August 18, 2021.[L51003]

  9. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    This biologic should come from recovered plasma from whole blood or prepared source plasma. the final product should not include any type of additives. … The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more of 17% should be globulin.

  10. Drug

    Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16714
    ApprovedInvestigational

    The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate. … sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from