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Ceftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalCeftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Tetracaine
go.drugbank.com/drugs/DB09085ApprovedInvestigationalVet approvedTetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
AG-702
go.drugbank.com/drugs/DB05836ExperimentalThis drug is developed by antigenics for the treatment of genital herpes infection and is under phase I of clinical trial.
Elafin
go.drugbank.com/drugs/DB05161InvestigationalElafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective tissue from destruction by the immune system.
CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalIt is converted by cellular esterases to CA-074.[A258234,A258239]
Fluorofuranylnorprogesterone F-18
go.drugbank.com/drugs/DB15282InvestigationalFluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).
Ixmyelocel-T
go.drugbank.com/drugs/DB17601InvestigationalDeveloped by Vericel Corporation, it is being investigated for cardiomyopathy.
Butyrylthiocholine
go.drugbank.com/drugs/DB04250ExperimentalA sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity.
Utidelone
go.drugbank.com/drugs/DB17575InvestigationalUtidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.
mRNA-3705
go.drugbank.com/drugs/DB17668InvestigationalDeveloped by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]