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Displaying results 2701 - 2710 of 3732 in total
  1. Drug

    Insulin tregopil

    go.drugbank.com/drugs/DB11568
    Investigational

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers
  2. Drug

    Rupatadine

    go.drugbank.com/drugs/DB11614
    ApprovedInvestigational

    Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates
  3. Drug

    Tucatinib

    go.drugbank.com/drugs/DB11652
    ApprovedInvestigational

    Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tuca...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  4. Drug

    Bryostatin 1

    go.drugbank.com/drugs/DB11752
    Investigational

    Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  5. Drug

    AZD-1305

    go.drugbank.com/drugs/DB11766
    Investigational

    AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Sarilumab

    go.drugbank.com/drugs/DB11767
    ApprovedInvestigational

    Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling

    Categories: Interleukin-6 Receptor Antagonist, Cytochrome P-450 CYP3A Inducers
  7. Drug

    Artefenomel

    go.drugbank.com/drugs/DB11809
    Investigational

    Artefenomel has been investigated for the treatment of Malaria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  8. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthrit...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  9. Drug

    Pritelivir

    go.drugbank.com/drugs/DB11844
    Investigational

    Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.

    Categories: P-glycoprotein substrates
  10. Drug

    Revefenacin

    go.drugbank.com/drugs/DB11855
    ApprovedInvestigational

    Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic ...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates