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Displaying results 2701 - 2710 of 10000 in total
  1. Drug

    Chlormerodrin

    go.drugbank.com/drugs/DB00534
    ApprovedWithdrawn

    Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. … It is no longer used and has been replaced with new classes of diuretic drugs.

  2. Drug

    Glucarpidase

    go.drugbank.com/drugs/DB08898
    ApprovedInvestigational

    [A7476,A7477] After the discovery of certain bacteria with the capacity to inactivate folate analogs such as methotrexate, carboxypeptidase G was identified and Carboxypeptidase G1 was first isolated … [L39855] Glucarpidase was first approved by the FDA in January 2012,[A7476] followed by the European Commission's approval in January 2022.[L39865] It is marketed as VORAXAZE.

  3. Drug

    Chromic chloride

    go.drugbank.com/drugs/DB09129
    Approved

    Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

    Mixtures: TRACUTIL® 10 ML AMPOLLAS, M T E 4 Concentrate Inj
  4. Target

    Beta-lactamase OXA-10

    go.drugbank.com/bio_entities/BE0001274
    TargetEnzymePseudomonas aeruginosa

    Hydrolyzes both carbenicillin and oxacillin.

    Polypeptides: Beta-lactamase OXA-10
  5. Drug

    Sipuleucel-T

    go.drugbank.com/drugs/DB06688
    ApprovedInvestigational

    Sipuleucel-T selectively targets the prostate-specific antigen (PSA) known as prostatic acid phosphatase (PAP) that is expressed in around 95% of prostate cancers. … In metastatic prostate cancer, it has extended survival by median 4.1 months (IMPACT Phase III trial data). Sipuleucel-T is marketed under the brand name Provenge by Dendreon Corporation.

  6. Target

    Cytosolic 10-formyltetrahydrofolate dehydrogenase

    go.drugbank.com/bio_entities/BE0000933
    TargetHumans

    Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).

    Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDH
  7. Target

    Bone morphogenetic protein 10

    go.drugbank.com/bio_entities/BE0010910
    TargetHumans

    Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors s...

    Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10
  8. Drug

    Meglumine

    go.drugbank.com/drugs/DB09415
    ApprovedInvestigational

    Mixtures: UROGRAFIN %76 IV ENJEKSIYON VE INFUZYON ICIN COZELTI, 100 ML, UROGRAFIN %76 IV ENJEKSIYON VE INFUZYON ICIN COZELTI, 50 ML
  9. Drug

    Phosphorus

    go.drugbank.com/drugs/DB14151
    Approved

    Mixtures: Liquid Calcium Mg Phosphorus and Vit.d-3, DECAVIT YUMUSAK KAPSUL, 30 ADET
  10. Drug

    Fluocortolone pivalate

    go.drugbank.com/drugs/DB15777
    Investigational

    Mixtures: DOLOPROCT KREM, 10 G, ULTRALAN KREM, 10 G