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Displaying results 2721 - 2730 of 10000 in total
  1. Drug

    Revefenacin

    go.drugbank.com/drugs/DB11855
    ApprovedInvestigational

    Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). … [A40026] It was developed by Theravance Biopharma and FDA approved on November 9, 2018.[L4818]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  2. Drug

    Citrus bioflavonoids

    go.drugbank.com/drugs/DB14586
    Approved

    Mixtures: VITAMIN C 1000 MG WITH BIOFLAVONOIDS 100 MG, Ester-C® 500 mg with Citrus Bioflavonoids Tablet
  3. Drug

    XT-150

    go.drugbank.com/drugs/DB21756
    Investigational

    XT-150 is a locally injectable non-viral therapy expressing IL-10v, a proprietary modified variant of IL-10.[L52125] It is being developed by Xalud Therapeutics.

    Synonyms: non-viral human interleukin-10 (IL-10) variant (IL-10var) encoding plasmid deoxyribonucleic acid (pDNA)
  4. Drug

    Zavegepant

    go.drugbank.com/drugs/DB15688
    ApprovedInvestigational

    mg bid) in subjects with mild allergic asthma. … trial (NCT04804033) is currently investigating the efficacy and safety of oral zavegepant in migraine prevention, and another one (NCT04987944) is evaluating the safety and efficacy of oral zavegepant (150

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl)-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)-
  5. Drug

    Thrombin

    go.drugbank.com/drugs/DB11300
    ApprovedInvestigational

    Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should not be re-exposed to the product [FDA Label]. … These antibodies may subsequently cross-react with endogenous human factor V and lead to its deficiency [FDA Label].

    Mixtures: ARTISS 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET, TISSEEL 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR 1 ADET
  6. Indication

    Eclampsia

    go.drugbank.com/conditions/DBCOND0000607
    Drugs: Cocarboxylase
    Synonyms: Eclampsia, unspecified as to time period
  7. Target

    Serine/threonine-protein kinase/endoribonuclease IRE1

    go.drugbank.com/bio_entities/BE0003839
    TargetHumans

    In unstressed cells, the endoplasmic reticulum luminal domain is maintained in its inactive monomeric state by binding to the endoplasmic reticulum chaperone HSPA5/BiP (PubMed:21317875). … Accumulation of misfolded proteins in the endoplasmic reticulum causes release of HSPA5/BiP, allowing the luminal domain to homodimerize, promoting autophosphorylation of the kinase domain and subsequent

    Synonyms: Endoplasmic reticulum-to-nucleus signaling 1
  8. Drug

    Maleic acid

    go.drugbank.com/drugs/DB04299
    Investigational

    Synonyms: cis-but-2-enedioic acid
  9. Indication

    Aspiration Pneumonia

    go.drugbank.com/conditions/DBCOND0031880
    Drugs: Prednisolone
    Synonyms: Pneumonitis due to inhalation of food and vomit
  10. Indication

    Influenza Type B

    go.drugbank.com/conditions/DBCOND0041710
    Drugs: Oseltamivir
    Synonyms: Influenza due to other identified influenza virus