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Exenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. … [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021.
Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analoguesSynonyms: Exendin 4, Exendin-4Amantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Synonyms: 1-adamantanamine, 1-adamantylamineMixtures: Innoprax-5, Osmolex ERBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological lactation after finding that bromocriptine was not shown to be safe for use.
Synonyms: 2-bromo-α-ergokryptin, 2-bromo-α-ergocryptineCategories: Serotonin 5-HT2 Receptor Agonists, P-glycoprotein inhibitorsMefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: N-(2,3-xylyl)-2-aminobenzoic acid, N-2,3-xylylanthranilic acidMethylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approvedMethylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s. … [L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.
Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inducersEribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. … Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic
Categories: Heterocyclic Compounds, 1-RingProducts: ERIBULINA EG, HALAVEN 0.5 mg/ml solution for injectionDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and promote to cell death. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]
Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexPermethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate, 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl esterAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235860,A235865] A meta-analysis of over 145,000 patients showed the risk of stroke in patients taking atenolol may depend on the age of the patient.
Mixtures: TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADET, TENORETIC 100 MG/25 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalDue to its duration of action of around 5 hours, NovoRapid is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from … If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening
Mixtures: RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADET, RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 Inducers