Search
Ethylenediamine
go.drugbank.com/drugs/DB14189ApprovedEthylenediamine is an organic compound that is used as a building block for the production of many other chemical products. … It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions [A34285].
Zidesamtinib
go.drugbank.com/drugs/DB21623ApprovedInvestigational[L63808] ROS1 gene fusions drive a small subset of non-small cell lung cancers, and while several ROS1 inhibitors are available, treatment is limited over time by two recurring problems: the emergence … Zidesamtinib is an orally administered ROS1 kinase inhibitor designed to remain active against ROS1 resistance mutations.
Ethylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalA narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. … It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products).
Synonyms: 3-O-Ethylmorphine, 3-ethoxymorphineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedSynonyms: HMD-PProducts: TECHNESCAN HDP FOR INJECTION 3 mg/vialImdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigational[L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … Imdevimab is a monoclonal antibody combined with [casirivimab] in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19.
Sertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineDelafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalDelafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections,
Categories: 4-Quinolones, Cytochrome P-450 CYP2C9 InducersEnsitrelvir
go.drugbank.com/drugs/DB18834ApprovedInvestigationalEnsitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: S-217622Methylchloroisothiazolinone
go.drugbank.com/drugs/DB14197ApprovedMethylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. … It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: 4-Isothiazolin-3-one, 5-chloro-2-methyl-, 5-Chloro-2-methyl-3(2H)-isothiazoloneBromothalonil
go.drugbank.com/drugs/DB14199ApprovedIt is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322]. … Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-(bromomethyl) glutaronitrile, 2-Bromo-2-(bromomethyl) pentanedinitrile