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Sodium chlorite
go.drugbank.com/drugs/DB13210InvestigationalFood and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413]. … Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S.
Arsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalThe enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Xanthan gum
go.drugbank.com/drugs/DB11253ApprovedIt is used as a thickening agent and stabilizer in emulsions.
Thioredoxin
go.drugbank.com/drugs/DB11298ApprovedIt plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin.
Raxtozinameran
go.drugbank.com/drugs/DB18228ApprovedInvestigationalRaxtozinameran is also known as Pfizer-BioNTech COVID-19 Vaccine and Comirnaty.
Roxithromycin
go.drugbank.com/drugs/DB00778ApprovedInvestigationalWithdrawnIt is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections.
Sodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnGold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Mitotane
go.drugbank.com/drugs/DB00648ApprovedInvestigationalMitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has...
Setiptiline
go.drugbank.com/drugs/DB09304ExperimentalSetiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
Centanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigationalreuptake inhibitor, positioning it as a new mechanistic option in a condition where response varies widely between individuals and many patients remain symptomatic on existing treatment. … [L63806,L63934] Established ADHD pharmacotherapy acts on norepinephrine and dopamine without a serotonergic component, and Otsuka describes centanafadine as the first and only approved norepinephrine-dopamine-serotonin