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RuvB-like 2
go.drugbank.com/bio_entities/BE0009019TargetHumansThe NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400 (PubMed:14966270). … May play a role in regulating the composition of the U5 snRNP complex (PubMed:28561026)
Synonyms: INO80 complex subunit JVardenafil
go.drugbank.com/drugs/DB00862ApprovedCompared to [sildenafil] and [tadalafil], vardenafil is a more potent inhibitor of PDE5; however, its selectivity for other PDE isoforms is lower than the one detected for tadalafil.
Categories: Genito Urinary System and Sex HormonesEfonidipine
go.drugbank.com/drugs/DB09235InvestigationalEfonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to ...
Categories: Membrane Transport ModulatorsBroxyquinoline
go.drugbank.com/drugs/DB13536ExperimentalCategories: Genito Urinary System and Sex HormonesCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalVitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results fro...
Mixtures: Se-Natal 19, Se-Plete DHACabergoline
go.drugbank.com/drugs/DB00248ApprovedInvestigationalCabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Categories: Genito Urinary System and Sex HormonesRelugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigational[L27996] In addition to its relative ease-of-use, relugolix was shown to be superior in the depression of testosterone levels when compared to [leuprolide], another androgen deprivation therapy used in
Categories: Sex Hormones and Insulins